New fields of research fields as diversified research in the late fifties and first half of the sixties were studying various types of medications such as antidepressants, anti-inflammatory drugs and cardiovascular diseases, antimicrobial agents and chemotherapy simultaneously. But it was not until the discovery of benzodiazepines and their inclusion in the clinic with the trade names Librium (Chlordiazepoxide, synthesized in 1955 and marketed from 1957) and Valium (Diazepam Diazepam in Mexico and released in 1963) that the company entered a period of such growth that quadrupled in a decade of investment in research and development. Valium was the flagship during the period that Roche wanted to call “The Age of benzodiazepines. In 1976 an accident at the factory in Seveso in Italy, affects Givaudan subsidiary, which in 2000 would be put in the bag and separate the Roche Group.In 1989, the company is restructured, appears Honlding Roche AG (Roche Holding SA), the same year was opened in Strasbourg the Roche International Clinical Research Center (International Center of Clinical Research Roche). In 1978 hits the market Rocaltrol (Calcitriol, an analogue of vitamin D). In 1980, Roche scientists isolated the pure alpha interferon with Genentech began working on the production of genetically concocted a version that gave birth to the product Roferon A, sales in 1986. The antibiotic Rocephin (ceftriaxone sodium), was launched in Switzerland in 1982 and by more than 18 years this was the main antibiotic and best-selling drug of all dem Roche products worldwide. In 1990 he introduced in the market Inhibace (cilazapril, a drug inhibitor of angiotensin converting enzyme) used for hypertension. In 1994, Roche acquired Syntex Corp. (headquartered in Palo Alto, CA) and the following year, Syntex was renamed Roche Bioscience.This unit is now known as Roche Palo Alto LLC Roche is one of the main research laboratories of the company. In 1999 the Food and Drug Administration of the USA. UU. authorizes Roche to produce Tamiflu, the only medication considered somewhat effective against H5N1 bird flu. In 2005 Roche sells vitamins division to Bayer, so the brand Redoxon passes to the latter.