What wrinkles? Studies have shown that facial muscles involuntarily cut about 15000 times a day, which leads to the formation of wrinkles and kinks in the dermis. Quite often, these wrinkles already in his youth, and with time increase. In children, skin folds when you laugh, cry, sorrow and other emotions to straighten out immediately after the cessation of muscle work. In adults, the sites where the most frequently arise folds gradually formed wrinkles, with an individual figure for each person. The degree of wrinkle formation influence and additional factors: the state of the epidermis and dermis matrix, the level of nutrition and metabolism in the deep layers of the skin, and as aggressive external factors to the skin (UV light, cold, bad makeup, environment, etc.). Rejuvenating the poison into medicine often there are cases where the poison in his skillful use becomes medicine. It happened with botulinum toxin type A.
Doctors who use it in neuroscience have noticed a side effect of the drug – the site of injection wrinkles. In the early 90-ies in the United States has been registered drug botox Company allergan, and in France – disport Company Beafor Ipsen International. Active ingredient in both drugs is one – botulinum toxin type A, but they differ in the number of albumin in disport him anymore. Later, the cream with Argireline (this see below) and the drug Refinex. Today, injections of botulinum toxin A has been a popular means of anti-age therapy. Principle of action of botulinum toxin A is simple: it blocks the release of acetylcholine in the neuromuscular synapse, which leads to muscle relaxation in the area of administration.